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Microsoft says its MAI-DxO system diagnosed up to 85% of NEJM case challenges

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Microsoft AI reported that its Diagnostic Orchestrator (MAI-DxO), a system that emulates a virtual panel of physicians working on top of language models, correctly diagnosed up to 85% of New England Journal of Medicine case records, more than four times the rate of a group of experienced physicians, and did so more cost-effectively.

Why it matters

Health systems weighing diagnostic AI got a benchmark built on real case records, though Microsoft notes the physicians worked without colleagues, textbooks or generative AI.

When
30 Jun 2025
ID
WTA-N-2025-0185
Who
Microsoft

Summary by wheresthe.ai, from Microsoft AI. Checked against the source on 9 Oct 2026.

Source copy: download the page as saved on 18 Oct 2026 (PDF). Also held by the Internet Archive.

Next stop on this Storyline: Led toMicrosoft’s MAI-DxO diagnosis results are published in Science and go to a hospital study

Cite this story

WTA-N-2025-0185: “Microsoft says its MAI-DxO system diagnosed up to 85% of NEJM case challenges.” wheresthe.ai, 30 Jun 2025. https://wheresthe.ai/d/us-microsoft-mai-dxo-diagnosis-2025-06/ (source: Microsoft AI).

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