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Arc Institute and NVIDIA release Evo 2, trained on DNA from 128,000 genomes

See how this story connects

Source: Arc Institute

Arc Institute, with NVIDIA and researchers from Stanford, UC Berkeley and UC San Francisco, released Evo 2, a biology model trained on more than 9.3 trillion nucleotides from over 128,000 genomes across all domains of life. Arc said it can identify disease-causing mutations in human genes and design genomes as long as those of simple bacteria; its code, data and weights are open.

Why it matters

Biologists gained an open model for reading and designing DNA at genome scale; Arc excluded pathogens that infect humans from its training data for safety.

When
19 Feb 2025
ID
WTA-N-2025-0175
Who
Arc Institute, NVIDIA

Summary by wheresthe.ai, from Arc Institute. Checked against the source on 9 Oct 2026.

Read the original at Arc Institute

Source copy: download the page as saved on 18 Oct 2026 (PDF). Also held by the Internet Archive.

Next stop on this Storyline: Led toAI-designed bacteriophages kill E. coli strains resistant to a natural phage

Cite this story

WTA-N-2025-0175: “Arc Institute and NVIDIA release Evo 2, trained on DNA from 128,000 genomes.” wheresthe.ai, 19 Feb 2025. https://wheresthe.ai/d/us-arc-evo-2-genome-model-2025-02/ (source: Arc Institute).

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