Latest
  1. Johns Hopkins Bayview tells 3,182 patients an employee put their health data into a public AI tool
  2. China’s AI compute access expected to double in 2027, with US-designed chips about 65 per cent
  3. UK commits £100m to national AI Biosecurity Lab
  4. Moonshot AI releases Kimi K3.1 Pro with 1-million-token context window
  5. Residents in Newport and Cardiff oppose hyperscale datacentres near homes
  6. Study: Grok 4.7 picked Republicans in 92% of forced midterm answers, GPT-6.1 Sol picked Democrats in 97%
  7. Attackers exploiting the PHP flaws hand the break-in to AI agents, Unit 42 says
  8. Elvis Presley’s rightsholders sue Anthropic over training on 274 songs

Latest / Science and research

ResearchScienceHealthUSConfirmed

RFdiffusion designs new proteins from scratch, Nature paper shows

See how this story connects

Source: Nature

David Baker’s group at the University of Washington’s Institute for Protein Design published RFdiffusion in Nature, a diffusion model built by fine-tuning RoseTTAFold that designs new protein backbones for binders, symmetric assemblies, enzyme active sites and therapeutic and metal-binding motifs. The software is openly available.

Why it matters

Protein designers gained an open tool to design binders and enzymes from scratch, work that fed into Baker’s share of the 2024 Nobel Prize in Chemistry.

When
11 Jul 2023
ID
WTA-N-2023-0180
Who
University of Washington Institute for Protein Design; David Baker

Summary by wheresthe.ai, from Nature. Checked against the source on 9 Oct 2026.

Read the original at Nature

Source copy: download the page as saved on 18 Oct 2026 (PDF). Document the source offers: document 1 (PDF). Also held by the Internet Archive.

Next stop on this Storyline: Built on byChemistry Nobel goes to Baker for protein design and to Hassabis and Jumper for AlphaFold

Cite this story

WTA-N-2023-0180: “RFdiffusion designs new proteins from scratch, Nature paper shows.” wheresthe.ai, 11 Jul 2023. https://wheresthe.ai/d/us-rfdiffusion-protein-design-2023-07/ (source: Nature).

Spotted an error? Email [email protected].